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KMID : 0877220060100020071
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Journal of Korean Epilepsy Society
2006 Volume.10 No. 2 p.71 ~ p.77
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Biostatistical Methods for Epilepsy Trials
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Myoung Sung-Min
Kim Shin-Young
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Abstract
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Clinical trial provide reliable basis for evaluating the efficacy and safty of new treatments. To proceed effectively with clinical trial requires an comprehension of the basic principles of clinical design and biostatistical methods. This review focuses on fundamentals of biostatistical theory, on studies of calculating sample size, on definitions for classsification of evidence in epilepsy trials and on examining biostatistical methods for evaluating efficacy of antiepileptic drugs. This review guide how to understand basic statistical concepts and types of study design for epilepsy trials.
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KEYWORD
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Epilepsy, Clinical trials, Biostatistics
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